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The Annals - 版本历史
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<strong>Annals of Oncology</strong>（通常简称 <strong>The Annals</strong> 或 <strong>Ann Oncol</strong>）是 <strong>[[ESMO]]</strong>（European Society for Medical Oncology，欧洲肿瘤内科学会）的官方旗舰月刊。近年来，该刊经历了爆发式增长，其影响因子（IF）飙升至 50 以上，超越了众多老牌刊物，成为能与 <strong>[[JCO]]</strong> 分庭抗礼的全球顶级肿瘤学期刊。作为欧洲肿瘤学的喉舌，它不仅发表改变临床实践的重磅 III 期临床试验（尤其是免疫治疗和靶向治疗），更是发布极具权威性的 <strong>[[ESMO临床实践指南]]</strong> 的核心平台。<br />
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<div style="font-size: 1.2em; font-weight: bold; letter-spacing: 1.2px;">Annals of Oncology</div><br />
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[[Image:Annals_of_Oncology_Logo.png|100px|ESMO 旗舰]]<br />
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<div style="font-size: 0.8em; color: #64748b; margin-top: 12px; font-weight: 600;">欧洲肿瘤学的最高殿堂</div><br />
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<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">1990年</td><br />
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<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #1e40af;">[[Elsevier]] (自2020年起)</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f1f5f9; color: #475569; border-bottom: 1px solid #e2e8f0;">协会隶属</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">[[ESMO]]</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f1f5f9; color: #475569; border-bottom: 1px solid #e2e8f0;">影响因子</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #b91c1c; font-weight: bold;">56.7 (2023 JCR)</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f1f5f9; color: #475569; border-bottom: 1px solid #e2e8f0;">主要对手</th><br />
<td style="padding: 6px 12px; border-bottom: 1px solid #e2e8f0; color: #0f172a;">JCO, Lancet Oncology</td><br />
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<th style="text-align: left; padding: 6px 12px; background-color: #f1f5f9; color: #475569;">核心标签</th><br />
<td style="padding: 6px 12px; color: #1e40af;">[[ESMO指南]], [[免疫治疗]]</td><br />
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在过去，肿瘤学界是 <em>JCO</em> 一家独大；而现在，<em>Annals of Oncology</em> 已经成长为与之并驾齐驱的巨头。该刊的特点是<strong>“快”</strong>和<strong>“精”</strong>。它设有快速通道（Fast Track），能让极具新闻价值的临床试验结果（如 ESMO 大会上的 Late-breaking abstracts）在几周内见刊。此外，它对<strong>[[精准肿瘤学]]</strong>（Precision Oncology）和生物标志物的转化研究给予了极高优先级的关注。<br />
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对于临床肿瘤医生和研发科学家来说，选择 JCO 还是 Annals of Oncology 往往取决于目标受众是侧重北美还是欧洲/亚洲。<br />
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<th style="padding: 12px; border: 1px solid #cbd5e1; color: #0f172a; width: 25%;">期刊</th><br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600; background-color: #ffffff;">[[Annals of Oncology]]</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1;">ESMO (欧洲)</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1; color: #b91c1c; font-weight:bold;">56.7</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1;"><strong>“欧洲旗舰”。</strong> 影响因子目前极高。是 <strong>[[ESMO指南]]</strong> 的发布地，这些指南在欧洲和亚洲的执行度极高。偏好转化医学和免疫治疗的新颖性。</td><br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600; background-color: #f8fafc;">[[JCO]]</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1;">ASCO (美国)</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1; color: #64748b;">42.1</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1;"><strong>“美国圣经”。</strong> 发文量大，覆盖面广。是 FDA 获批药物 pivotal trials 的主要阵地。是 ASCO 指南的发布地。</td><br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600; background-color: #ffffff;">[[Lancet Oncology]]</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1;">Lancet Grp</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1; color: #64748b;">41.6</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1;"><strong>“全球政策”。</strong> 关注全球卫生和政策。拥有强大的新闻和评论板块。在临床试验外，更关注社会议题。</td><br />
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<td style="padding: 10px; border: 1px solid #cbd5e1; font-weight: 600; background-color: #f8fafc;">[[Cancer Discovery]]</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1;">AACR</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1; color: #64748b;">28.0</td><br />
<td style="padding: 8px; border: 1px solid #cbd5e1;"><strong>“转化先锋”。</strong> AACR 会刊。比 Annals 和 JCO 更偏向基础机制和早期药物研发（Phase I/Pre-clinical）。</td><br />
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ESMO 指南以“简明、实用”著称，通常包括极其清晰的<strong>[[治疗流程图]]</strong>（Algorithms）和<strong>[[ESMO-MCBS]]</strong>（临床获益量表）评分。对于许多非美国医生来说，ESMO 指南的可操作性甚至高于 NCCN 指南。<br />
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<span style="color: #0f172a; font-weight: bold; font-size: 1.05em; display: inline-block; margin-bottom: 15px;">关键参考文献</span><br />
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[1] <strong>Cherny NI, et al. (2015).</strong> <em>A standardised, generic, validated approach to stratify the magnitude of clinical benefit... (ESMO-MCBS).</em> <strong>[[Ann Oncol]]</strong>.<br><br />
<span style="color: #475569;">[评分标准]：这篇论文提出了 <strong>[[ESMO-MCBS]]</strong> 量表，成为全球评估抗癌新药是否“物有所值”（具有实质性临床获益）的黄金标准。</span><br />
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[2] <strong>Powles T, et al. (2020).</strong> <em>Avelumab maintenance therapy for advanced or metastatic urothelial carcinoma (JAVELIN Bladder 100).</em> <strong>[[NEJM]]</strong> / <strong>[[Ann Oncol]]</strong> (Sub-analysis).<br><br />
<span style="color: #475569;">[临床试验]：大量关于 <strong>[[免疫检查点抑制剂]]</strong>（如 PD-1/PD-L1）在肺癌、尿路上皮癌中的重磅试验数据，经常选择在 Annals of Oncology 上发表。</span><br />
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Annals of Oncology · 知识图谱<br />
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<td style="padding: 10px 15px; color: #334155;">[[ESMO]] (European Society for Medical Oncology)</td><br />
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<td style="padding: 10px 15px; color: #334155;">[[ESMO指南]] • [[免疫相关不良反应]] • [[精准医疗]]</td><br />
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<td style="padding: 10px 15px; color: #334155;">[[JCO]] • [[The Lancet Oncology]] • [[Nature Cancer]]</td><br />
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<td style="padding: 10px 15px; color: #334155;">[[ESMO Open]] (Gold OA)</td><br />
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