https://www.yiliao.com/index.php?action=history&feed=atom&title=%E8%A1%80%E6%A0%93%E7%B4%A0A2 2026-04-18T02:04:23Z 本wiki的该页面的版本历史 MediaWiki 1.35.1 https://www.yiliao.com/index.php?title=%E8%A1%80%E6%A0%93%E7%B4%A0A2&diff=304374&oldid=prev 2021-07-21T18:25:35Z

<p>建立内容为“{{chembox | verifiedrevid = 411950909 | ImageFile = Thromboxane A2 acsv.svg | ImageSize = | ImageFileL2 = ThromboxaneA2 spacefill.png | ImageFileR2 = ThromboxaneA…”的新页面</p> <p><b>新页面</b></p><div>{{chembox<br /> | verifiedrevid = 411950909<br /> | ImageFile = Thromboxane A2 acsv.svg<br /> | ImageSize =<br /> | ImageFileL2 = ThromboxaneA2 spacefill.png<br /> | ImageFileR2 = ThromboxaneA2.png<br /> | IUPACName =<br /> | OtherNames =<br /> | Section1 = {{Chembox Identifiers<br /> | CASNo = 57576-52-0<br /> | PubChem = 5280497<br /> | SMILES =<br /> | MeSHName = Thromboxane+A2<br /> }}<br /> | Section2 = {{Chembox Properties<br /> | Formula = {{碳|20}}{{氢|32}}{{氧|5}}<br /> | MolarMass = 352.465 g/mol<br /> | Appearance =<br /> | Density =<br /> | MeltingPt =<br /> | BoilingPt =<br /> | Solubility =<br /> }}<br /> | Section3 = {{Chembox Hazards<br /> | MainHazards =<br /> | FlashPt =<br /> | Autoignition =<br /> }}<br /> }}<br /> <br /> '''血栓素A2'''是一种[[血栓素]]，常用作[[血管收缩剂]]，可以激活[[血小板]]、使其聚集，是治愈组织损伤和[[发炎]]的常用药。但也会导致[[心绞痛]]。<br /> <br /> 血栓素A2通过血栓素A[[合酶]]由[[前列腺素H2]]产生，在水溶液中极不稳定，30秒内将水解成[[血栓素B2]]。因此主要以组织附近的[[自分泌]]或[[旁分泌]]中介的方式作用。而其相关研究也是用类似物U46619和I-BOP来做的。&lt;ref&gt;{{cite article|title=Thromboxane A2-induced contraction of rat caudal arterial smooth muscle involves activation of Ca2+ entry and Ca2+sensitization: Rho-associated kinase-mediated phosphorylation of MYPT1 at Thr-855 but not Thr-697|author=Michael P. Walsh, et all|url=http://biosupport.licor.com/docs/2005/BJ20050237.pdf}}&lt;/ref&gt; [[人体实验]]中，依照11去氢[[血栓烷]]B2的等级来测试血栓素A2的产生。&lt;ref&gt;{{cite journal|title=11-Dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation|author=Catella F, Healy D, Lawson JA, FitzGerald GA|journal=PNAS|year=1986|volume=83|issue=16|pages=5861–5865|url=http://www.pnas.org/content/83/16/5861.abstract|pmid=3461463|doi=10.1073/pnas.83.16.5861|pmc=386396}}&lt;/ref&gt;&lt;ref&gt;{{cite journal|author=Lordkipanidzé M, Pharand C, Schampaert E, Turgeon J, Palisaitis DA, Diodati JG|title=A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease|journal=Eur Heart J|year=2007|volume=28|issue=14|pages=1702–1708|doi=10.1093/eurheartj/ehm226|pmid=17569678}}&lt;/ref&gt;<br /> <br /> == 参考文献 ==<br /> <br /> {{reflist}}<br /> {{类花生酸类}}<br /> <br /> [[Category:类花生酸]]<br /> <br /> ==参考来源==<br /> *[http://zh.wikipedia.org/wiki/%E8%A1%80%E6%A0%93%E7%B4%A0A2 维基百科-血栓素A2]</div>

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