123.130.221.191：建立内容为“{{Infobox disease | Name = Encephalitis lethargica | Image = Economo.jpg | Caption = 首先描述此病的Constantin von Economo…”的新页面

2021-07-21T16:21:02Z

建立内容为“{{Infobox disease | Name = Encephalitis lethargica | Image = Economo.jpg | Caption = 首先描述此病的Constantin von Economo…”的新页面

新页面

{{Infobox disease |
Name = Encephalitis lethargica |
Image = Economo.jpg |
Caption = 首先描述此病的[[Constantin von Economo]] |
DiseasesDB = 32498 |
ICD10 = {{ICD10|A|85|8|a|80}}
|

ICD9 = {{ICD9|049.8}} |
ICDO = |
OMIM = |
MedlinePlus = |
eMedicineSubj = |
eMedicineTopic = |
MeshID = |

}}
'''流行性脑炎'''或'''甲型脑炎'''是一种非典型的脑炎，又称为'''嗜睡性脑炎'''（但不是由采采[[蝇]]（tsetse fly）传播的非洲[[昏睡症]]）。此病最先由[[神经学家]]Constantin von Economo于1917年报告。<ref>{{WhoNamedIt|synd|3356}}</ref><ref>K. von Economo. Encepahlitis lethargica. ''Wiener klinische Wochenschrift'', May 10, 1917, 30: 581-585. Die Encephalitis lethargica. Leipzig and Vienna, Franz Deuticke, 1918.</ref> 此病影响[[大脑]]，令一些病人不能说话，甚至不能移动。<ref name=Dale_2004>{{cite journal | author = Dale RC, Church AJ, Surtees RA, ''et al.'' | title = Encephalitis lethargica syndrome: 20 new cases and evidence of basal ganglia autoimmunity | journal = Brain | volume = 127 | issue = Pt 1 | pages = 21–33 | year = 2004 | url = http://brain.oxfordjournals.org/cgi/content/full/127/1/21 | pmid = 14570817 | doi = 10.1093/brain/awh008}}</ref> 在1915年到1926年间，<ref>{{DorlandsDict|nine/000952335|Encephalitis lethargica}}</ref> 该疾病曾经发生全球性的[[大流行]]；而之后只有零星个案而没有再爆发。<ref name=Stryker_1925>{{cite journal | author = Stryker Sue B. | title = Encephalitis lethargica: the behavior residuals | journal = Training School Bulletin | volume = 22 | issue = 1925 | pages = 152–7}}</ref><ref name=Reid_2001>{{cite journal | author = Reid AH, McCall S, Henry JM, Taubenberger JK | title = Experimenting on the past: the enigma of von Economo's encephalitis lethargica | journal = J. Neuropathol. Exp. Neurol. | volume = 60 | issue = 7 | pages = 663–70 | year = 2001 | pmid = 11444794 | doi = }}</ref>

==症状==

流行性脑炎的症状为[[发热|发高烧]]、[[喉咙痛]]、[[头痛]]、重影（Double vision）、动作及思想迟缓、日夜巅倒（sleep inversion）, [[紧张症]]（catatonia）和[[疲劳]]<ref name=Dale_2004/>。一些急症病人可能进入类似[[昏迷]]的状态。病人的眼也可能出现不正常的运动、<ref name="pmid16200538">{{cite journal |author=Vilensky JA, Goetz CG, Gilman S |title=Movement disorders associated with encephalitis lethargica: a video compilation |journal=Mov. Disord. |volume=21 |issue=1 |pages=1–8 |year=2006 |month=January |pmid=16200538 |doi=10.1002/mds.20722}}</ref>[[柏金逊症]]（parkinsonism）、上半身[[无力]]、[[肌肉痛]]、[[手震]]、[[颈部僵硬]]和行动[[变异]]（如[[思觉失调]]）。

患者可能会在短至一年后患上脑炎后型巴金森症。

==病因==

流行性脑炎的病因未明。<ref name="pmid18569452">{{cite journal |author=McCall S, Vilensky JA, Gilman S, Taubenberger JK |title=The relationship between encephalitis lethargica and influenza: a critical analysis |journal=J. Neurovirol. |volume=14 |issue=3 |pages=177–85 |year=2008 |month=May |pmid=18569452 |doi=10.1080/13550280801995445 |url=http://www.informaworld.com/openurl?genre=article&doi=10.1080/13550280801995445&magic=pubmed&#124;&#124;1B69BA326FFE69C3F0A8F227DF8201D0 |pmc=2778472}}</ref>

2004年的一个研究认为是由于[[免疫反应]]。

==参见==

[[Image:Encephalitis-livre.gif|thumb|Encephalitis lethargica. Its sequelae and treatment - Constantin Von Economo, 1931:封面]]
{{Reflist}}

==外部连结==
*[http://www.ninds.nih.gov/health_and_medical/disorders/encephalitis_lethargica.htm National Institute of Neurological Disorders and Stroke]
*[http://news.bbc.co.uk/1/hi/health/3930727.stm Mystery of the Forgotten Plague]: BBC news item about the tracing of the infectious agent in encephalitis lethargica

[[Category:炎症]] [[Category:神经系统疾病]]
==参考来源==
*[http://zh.wikipedia.org/wiki/%E6%B5%81%E8%A1%8C%E6%80%A7%E8%85%A6%E7%82%8E 维基百科-流行性腦炎]

流行性脑炎 - 版本历史

123.130.221.191：建立内容为“{{Infobox disease | Name = Encephalitis lethargica | Image = Economo.jpg | Caption = 首先描述此病的Constantin von Economo…”的新页面