https://www.yiliao.com/index.php?action=history&feed=atom&title=%E4%B9%99%E9%85%B0%E4%B9%99%E9%85%B0%E8%BE%85%E9%85%B6A 2026-04-19T07:42:14Z 本wiki的该页面的版本历史 MediaWiki 1.35.1 https://www.yiliao.com/index.php?title=%E4%B9%99%E9%85%B0%E4%B9%99%E9%85%B0%E8%BE%85%E9%85%B6A&diff=305055&oldid=prev 2021-07-21T18:44:58Z

<p>建立内容为“{{chembox | Verifiedfields = changed | verifiedrevid = 477239005 |ImageFile=Acetoacetyl coenzyme A.svg |ImageSize=300px |IUPACName= |OtherNames= |Section1= {{Chem…”的新页面</p> <p><b>新页面</b></p><div>{{chembox<br /> | Verifiedfields = changed<br /> | verifiedrevid = 477239005<br /> |ImageFile=Acetoacetyl coenzyme A.svg<br /> |ImageSize=300px<br /> |IUPACName=<br /> |OtherNames=<br /> |Section1= {{Chembox Identifiers<br /> | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}<br /> | ChemSpiderID = 83198<br /> | InChI = 1/C25H40N7O18P3S/c1-13(33)8-16(35)54-7-6-27-15(34)4-5-28-23(38)20(37)25(2,3)10-47-53(44,45)50-52(42,43)46-9-14-19(49-51(39,40)41)18(36)24(48-14)32-12-31-17-21(26)29-11-30-22(17)32/h11-12,14,18-20,24,36-37H,4-10H2,1-3H3,(H,27,34)(H,28,38)(H,42,43)(H,44,45)(H2,26,29,30)(H2,39,40,41)/t14-,18-,19-,20+,24-/m1/s1<br /> | InChIKey = OJFDKHTZOUZBOS-CITAKDKDBD<br /> | StdInChI_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChI = 1S/C25H40N7O18P3S/c1-13(33)8-16(35)54-7-6-27-15(34)4-5-28-23(38)20(37)25(2,3)10-47-53(44,45)50-52(42,43)46-9-14-19(49-51(39,40)41)18(36)24(48-14)32-12-31-17-21(26)29-11-30-22(17)32/h11-12,14,18-20,24,36-37H,4-10H2,1-3H3,(H,27,34)(H,28,38)(H,42,43)(H,44,45)(H2,26,29,30)(H2,39,40,41)/t14-,18-,19-,20+,24-/m1/s1<br /> | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}<br /> | StdInChIKey = OJFDKHTZOUZBOS-CITAKDKDSA-N<br /> | CASNo_Ref = {{cascite|changed|??}}<br /> | CASNo=1420-36-6<br /> | PubChem=74<br /> | ChEBI_Ref = {{ebicite|correct|EBI}}<br /> | ChEBI = 15345<br /> | SMILES = O=C(C)CC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n2cnc1c(ncnc12)N)[C@H](O)[C@@H]3OP(=O)(O)O<br /> | MeSHName=acetoacetyl+CoA<br /> }}<br /> |Section2= {{Chembox Properties<br /> | Formula=C&lt;sub&gt;25&lt;/sub&gt;H&lt;sub&gt;40&lt;/sub&gt;N&lt;sub&gt;7&lt;/sub&gt;O&lt;sub&gt;18&lt;/sub&gt;P&lt;sub&gt;3&lt;/sub&gt;S<br /> | MolarMass=851.609 g/mol<br /> | Appearance=<br /> | Density=<br /> | MeltingPt=<br /> | BoilingPt=<br /> | Solubility=<br /> }}<br /> |Section3= {{Chembox Hazards<br /> | MainHazards=<br /> | FlashPt=<br /> | Autoignition=<br /> }}<br /> }}<br /> '''乙酰乙酰辅酶A'''（{{lang-en|Acetoacetyl CoA}}）是[[甲羟戊酸途径]]中合成β-羟基-β-甲[[戊二酸]]单酰[[辅酶A]]（HMG-[[CoA]]）的[[前体]]，是[[胆固醇]]合成的必要物质，在[[肝脏]]中的[[酮体]]合成里也有一定作用。在组织中的酮体分解途径中，它的合成与分解则与HMG-CoA无关。<br /> <br /> 它由{{le|硫解酶|thiolase}}合成两[[分子]][[乙酰辅酶A]]而来，再由{{le|β-羟-β-甲戊二酸单酰辅酶A合酶|HMG-CoA synthase}}与一分子乙酰辅酶A合成HMG-CoA。而在[[亮氨酸]]的[[代谢]]过程中，上述反应按相反方向进行。<br /> <br /> [[File:MevalonatePathway zh.png|550px|thumb|center|甲羟戊酸途径]]<br /> <br /> ==另见==<br /> * [[甲羟戊酸途径]]<br /> * [[乙酰乙酸]]<br /> * {{le|β-羟基丁酰基辅酶A脱氢酶|Beta-hydroxybutyryl-CoA dehydrogenase}}<br /> <br /> {{Cholesterol metabolism intermediates}}<br /> <br /> [[Category:辅酶A硫酯]]<br /> <br /> ==参考来源==<br /> *[http://zh.wikipedia.org/wiki/%E4%B9%99%E9%85%B0%E4%B9%99%E9%85%B0%E8%BE%85%E9%85%B6A 维基百科-乙酰乙酰辅酶A]</div>

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